Todd Hollon

Assistant Professor
University of Michigan
tocho (at) umich.edu


Visual Intelligence

  1. Yiwei Lyu, Chenhui Zhao, Soumyanil Banerjee, Shixuan Liu, Akshay T. Rao, Akhil Kondepudi, Honglak Lee, and Todd C. Hollon
    COMPUTER VISION AND PATTERN RECOGNITION · 2026

    Standard contrastive language-image pre-training can neglect objects in visual scenes. ItemizedCLIP forces models to learn and attend to all described items, resulting in better visual representations.


  2. Xinhai Hou, Shaoyuan Xu, Manan Biyani, Moyan Li, Jia Liu, Todd C. Hollon, and Bryan Wang
    COMPUTER VISION AND PATTERN RECOGNITION · 2026

    Recent visual agents can score well while using image tools unfaithfully-e.g., cropping irrelevant regions or ignoring tool outputs. CodeV represents tools as executable Python code and trains with Tool-Aware Policy Optimization (TAPO), using process-level rewards on visual tool inputs and outputs to improve both accuracy and faithful tool use on search and broader multimodal benchmarks.


  3. Shixuan Liu*, Daniel A. Li*, Yiwei Lyu, Akhil Kondepudi, Honglak Lee, and Todd C. Hollon
    NEURIPS UNIREPS WORKSHOP · 2025

    CLIPred is a framework that jointly optimizes the I-JEPA self-supervision and CLIP language supervision objectives for visual representation learning, outperforming either alone and achieving better zero-shot transfer than DINOv2+CLIP at lower training cost.


  4. Yiwei Lyu, Sung Jik Cha, Cheng Jiang, Asadur Chowdury, Xinhai Hou, Edward Harake, Akhil Kondepudi, Christian Freudiger, Honglak Lee, and Todd C. Hollon
    AAAI · 2025

    This paper introduces Restorative Step-Calibrated Diffusion (RSCD) for biomedical optical image restoration, improving reconstruction fidelity by adapting denoising dynamics to the characteristics of microscopy data.


  5. Shixuan Liu, Yiwei Lyu, Honglak Lee, and Todd C. Hollon
    NEURIPS FITML WORKSHOP · 2024

    SimCLIP is a generalized framework for CLIP fine-tuning that constructs minibatches containing clusters of similar image-text pairs to produce harder in-batch negatives, improving downstream performance over standard CLIP fine-tuning without hand-crafted hard negative captions.


  6. Cheng Jiang, Alexander Gedeon, Yiwei Lyu, Eric Landgraf, Yufeng Zhang, Xinhai Hou, Akhil Kondepudi, Asadur Chowdury, Honglak Lee, and Todd C. Hollon
    CVPR WORKSHOP · 2024

    This work proposes Masked Slice Diffusion for Super-Resolution (MSDSR), a strategy for volumetric biomedical super-resolution trained with only 2D supervision, enabling high-quality 3D reconstruction when fully paired 3D labels are scarce.


  7. Xinhai Hou *, Cheng Jiang*, Akhil Kondepudi, Yiwei Lyu, Asadur Zaman Chowdury, Honglak Lee, and Todd C. Hollon
    ARXIV · 2024

    This study introduces Slide Pre-trained Transformers (SPT), a self-supervised framework for whole-slide representation learning that captures multiscale histologic structure to support downstream pathology tasks with limited manual annotation.


  8. Cheng Jiang*, Xinhai Hou*, Akhil Kondepudi, Asadur Chowdury, Christian W. Freudiger, Daniel A. Orringer, Honglak Lee, and Todd C. Hollon
    COMPUTER VISION AND PATTERN RECOGNITION · 2023

    HiDisc is a self-supervised learning method that leverages the inherent patient-slide-patch hierarchy of biomedical microscopy to learn stronger visual representations without explicit negative mining.


  9. Cheng Jiang*, Asadur Chowdury*, Xinhai Hou*, Akhil Kondepudi, Christian W. Freudiger, Kyle Conway, Sandra Camelo-Piragua, Daniel A. Orringer, Honglak Lee, and Todd C. Hollon
    NEURIPS DATASETS & BENCHMARKS · 2022

    OpenSRH is the first public dataset of clinical stimulated Raman histology images from brain tumor patients, released alongside benchmarks to accelerate machine learning research for intraoperative brain tumor diagnosis.


  10. Esteban Urias, Christopher Freudiger, Daniel Orringer, Honglak Lee, and Todd Hollon
    MLHC · 2020

    This paper develops a weakly supervised denoising approach for stimulated Raman histology, improving image quality in label-free optical microscopy of human brain tumor specimens.


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